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Summary
I was a graduate student with Dr. David A. Jackson in the Deptartment of Microbiology and Immunology at the University of Michigan Medical School. My PhD work focused on the molecular genetics of phage P22 and the use of SV40 as a vector for the introduction of genes into animal cells. My postdoctoral work was with Dr. Harvey Lodish in the Department of Biology at MIT and the Whitehead Institute. My work there focused on the molecular genetics of the cellular slime mold Dictyostelium discoideum. I began on the faculty at Northwestern in the Department of Cell Biology and Anatomy (which became the Department of Cell and Molecular Biology) as an assistant professor in 1984. The main focus of my research lab through 2005 was the role of molecular motors in cell migration. We used both cultured mammalian cells and Dictyostelium in these studies. In 2000 I became the founding director of the Center for Genetic Medicine a cross campus Center that currently has 140 faculty members in 18 different departments in four different schools at Northwestern University. The Center for Genetic Medicine provides an umbrella for genetics and genomics throughout the University. You can learn more about the Genetic Center.
I was a graduate student with Dr. David A. Jackson in the Deptartment of Microbiology and Immunology at the University of Michigan Medical School. My PhD work focused on the molecular genetics of phage P22 and the use of SV40 as a vector for the introduction of genes into animal cells. My postdoctoral work was with Dr. Harvey Lodish in the Department of Biology at MIT and the Whitehead Institute. My work there focused on the molecular genetics of the cellular slime mold Dictyostelium discoideum. I began on the faculty at Northwestern in the Department of Cell Biology and Anatomy (which became the Department of Cell and Molecular Biology) as an assistant professor in 1984. The main focus of my research lab through 2005 was the role of molecular motors in cell migration. We used both cultured mammalian cells and Dictyostelium in these studies. In 2000 I became the founding director of the Center for Genetic Medicine a cross campus Center that currently has 140 faculty members in 18 different departments in four different schools at Northwestern University. The Center for Genetic Medicine provides an umbrella for genetics and genomics throughout the University. You can learn more about the Genetic Center.
| Current Institution | Northwestern University |
| Current School | Feinberg School of Medicine |
| Department | Medicine |
| Disciplines | |
| Address | 303 E. Superior St., Lurie 7-125 Chicago Illinois 60611 United States Phone: (312) 503-3209 |
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Education
University of Michigan
Ph.D.
Work Experience
Professor
Feinberg School of Medicine, Northwestern University
Director
Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University
Dean for research
Feinberg School of Medicine, Northwestern University
(Jul 2007 - Present)
Achievements
General
Publication Summary
Publications
- Richard S. Pollenz, Tung-Ling L. Chen, Leda Trivinos-Lagos and Rex L. Chisholm. 1992. The Dictyostelium essential light chain is required for myosin function. Cell 69, 951-962.
- Pengxin Chen, Bruce D. Ostrow, Sherrie R. Tafuri and Rex L. Chisholm. 1994. Targeted disruption of the Dictyostelium RMLC gene produces cells defective in cytokinesis and development. J. Cell Biol. 127, 1933-1944.
- Bruce D. Ostrow, Pengxin Chen, and Rex L. Chisholm. 1994. Expression of a myosin regulatory light chain phosphorylation site mutant complements the cytokinesis and developmental defects of Dictyostelium RMLC null cells. J. Cell Biol. 127, 1945-1955.
- Tung-Ling L. Chen, Wendy A. Wolf and Rex L. Chisholm. 1998. Cell type specific rescue of myosin function during Dictyostelium development defines two distinct cell movements required for culmination. Development 125, 3895-3903.
- Shuo Ma, Leda Trivinos-Lagos, Ralph Graf and Rex L. Chisholm. 1999. Dynein intermediate chain mediated dynein-dynactin interaction is required for interphase microtubule organization and centrosome replication and separation in Dictyostelium. J. Cell Biol. 147, 1261-1274.
- Bernard M. Chaudoir, Patricia A. Kowalczyk and Rex L. Chisholm. 1999. Myosin regulatory light chain mutation affect enzyme function and kinetics. J. Cell Sci. 112, 1611-1620.
- Wendy A. Wolf, Teng-Leong Chew and Rex L. Chisholm. 1999. Regulation of cytokinesis. Cell. Mol. Life Sci. 55, 108-120.
Books
Other Publications
