Peer reviewed pubblications      

[1] Lizard G, Rouaud O, Demarquoy J, Cherkaoui-Malki M, Iuliano L (2012) Potential Roles of Peroxisomes in Alzheimer's Disease and in Dementia of the Alzheimer's Type. J Alzheimers Dis (in press),

[2] Jean-Luc Cracowski BD, François Chabot, José Labarere, Edzard Schwedhelm, Denis Monneret, Luigi Iuliano, Christophe Pison, Ari Chaouat, Martine Reynaud-Gaubert, Patrice Faure, Renke Maas, Jean-Charles Renversez, Claire Cracowski, Olivier Sitbon, Gerald Simmoneau, Azzedine Yaici, Marc Humbert. (2012) Urinary F2-isoprostanes, a biomarker of lipid peroxidation, independently correlate with survival in a multicenter prospective cohort of incident pulmonary arterial hypertension. Chest (in press),

[3] Galli F, Battistoni A, Gambari R, Pompella A, Bragonzi A, Pilolli F, Iuliano L, Piroddi M, Dechecchi MC, Cabrini G (2012) Oxidative stress and antioxidant therapy in cystic fibrosis. Biochim Biophys Acta (in press),

[4] Straface G, Biscetti F, Pitocco D, Bertoletti G, Misuraca M, Vincenzoni C, Snider F, Arena V, Stigliano E, Angelini F, Iuliano L, Boccia S, de Waure C, Giacchi F, Ghirlanda G, Flex A (2011) Assessment of the genetic effects of polymorphisms in the osteoprotegerin gene, TNFRSF11B, on serum osteoprotegerin levels and carotid plaque vulnerability. Stroke 42, 3022-3028.

[5] Pigna G, Napoli A, Zaccagna F, Marincola BC, Monticolo R, Catalano C, Iuliano L, Arca M (2011) The relationship between metabolic syndrome, its components, and the whole-body atherosclerotic disease burden as measured by computed tomography angiography. Atherosclerosis 215, 417-420.

[6] Iuliano L, Misuraca M, Varroni A, Raponi M, Massucci M, Pagnanelli A, Cimino G, Bertoletti G (2011) Multiple thromboembolism with multiple causes in a 69-year-old woman: a case report. J Med Case Reports 5, 186.

[7] Iuliano L (2011) Pathways of cholesterol oxidation via non-enzymatic mechanisms. Chem Phys Lipids 164, 457-468.

[8] Schmitz G, Lizard G, Iuliano L (2010) Special issue to LipidomicNet and ENOR joint Workshop (19-20 November 2010; Munich, Germany) "Analysis and function of oxysterols and other regulatory and lipotoxic molecular lipid species". Chem Phys Lipids 164, 409-410.

[9] Iuliano L, Monticolo R, Straface G, Spoletini I, Gianni W, Caltagirone C, Bossu P, Spalletta G (2010) Vitamin E and Enzymatic/Oxidative Stress-Driven Oxysterols in Amnestic Mild Cognitive Impairment Subtypes and Alzheimer's Disease. J Alzheimers Dis

[10] Galli F, Iuliano L (2010) La supplementazione umana con vitamina E. Progress in Nutrition 12, 219-234.

[11] Galli F, Iuliano L (2010) Do statins cause myopathy by lowering vitamin E levels? Med Hypotheses 74, 707-709.

[12] Anticoli S, Arciello M, Mancinetti A, De Martinis M, Ginaldi L, Iuliano L, Balsano C (2010) 7-ketocholesterol and 5,6-secosterol modulate differently the stress-activated mitogen-activated protein kinases (MAPKs) in liver cells. J Cell Physiol 222, 586-595.

[13] Napoli A, Catalano C, Francone M, Sciacca V, Carbone I, Greco C, Anzidei M, Calabrese FA, Marincola BC, Kirchin MA, Vestri A, Arca M, Iuliano L, Passariello R (2009) Imaging coronary and extracoronary atherosclerosis: feasibility and impact of whole-body computed tomography angiography. Eur Radiol 19, 1704-1714.

[14] Iuliano L, Monticolo R, Straface G, Zullo S, Galli F, Boaz M, Quattrucci S (2009) Association of cholesterol oxidation and abnormalities in fatty acid metabolism in cystic fibrosis. Am J Clin Nutr 90, 477-484.

[15] Iuliano L, Micheletta F, Napoli A, Catalano C (2009) Myocardial infarction with normal coronary arteries: a case report and review of the literature. J Med Case Reports 3, 24.

[16] Iuliano L, Di Matteo A, Straface G (2009) Management of nonvalvular atrial fibrillation: a comprehensive approach. Indian J Med Sci 63, 419-430.

[17] Biscetti F, Straface G, Arena V, Stigliano E, Pecorini G, Rizzo P, De Angelis G, Iuliano L, Ghirlanda G, Flex A (2009) Pioglitazone enhances collateral blood flow in ischemic hindlimb of diabetic mice through an Akt-dependent VEGF-mediated mechanism, regardless of PPARgamma stimulation. Cardiovasc Diabetol 8, 49.

[18] Francone M, Di Castro E, Napoli A, Bolzan C, Carbone I, Bertoletti L, Iuliano L, Catalano C, Passariello R (2008) Dose reduction and image quality assessment in 64-detector row computed tomography of the coronary arteries using an automatic exposure control system. J Comput Assist Tomogr 32, 668-678.

[19] Larsson H, Bottiger Y, Iuliano L, Diczfalusy U (2007) In vivo interconversion of 7beta-hydroxycholesterol and 7-ketocholesterol, potential surrogate markers for oxidative stress. Free Radic Biol Med 43, 695-701.

[20] Iuliano L, Micheletta F, Natoli S, Tramaglino L, Greco C, Modesti PA (2007) Aortic coarctation in the elderly: how many errors lie behind an unexpected diagnosis? Intern Emerg Med 2, 207-209.

[21] Arca M, Natoli S, Micheletta F, Riggi S, Di Angelantonio E, Montali A, Antonini TM, Antonini R, Diczfalusy U, Iuliano L (2007) Increased plasma levels of oxysterols, in vivo markers of oxidative stress, in patients with familial combined hyperlipidemia: reduction during atorvastatin and fenofibrate therapy. Free Radic Biol Med 42, 698-705.

[22] Micheletta F, Iuliano L (2006) Free Radical Attack on Cholesterol: Oxysterols as Markers of Oxidative Stress and as Bioactive Molecules. Immunol Endocr Metabol Agents Med Chem 6, 305-316.

[23] Micheletta F, Natoli S, Iuliano L (2005) Implantable cardioverter-defibrillator therapy after myocardial infarction. N Engl J Med 352, 1039-1041; author reply 1039-1041.

[24] Corradini SG, Micheletta F, Natoli S, Iappelli M, Di Angelantonio E, De Marco R, Elisei W, Siciliano M, Rossi M, Berloco P, Attili AF, Diczfalusy U, Iuliano L (2005) High preoperative recipient plasma 7beta-hydroxycholesterol is associated with initial poor graft function after liver transplantation. Liver Transpl 11, 1494-1504.

[25] Boaz M, Iuliano L, Himmelfarb J, Matas Z, Micheletta F, McMonagle E, Friedman V, Natoli S, Gvirtz G, Biro A, Smetana S, Sabo G, Gafter U, Weinstein T (2005) Baseline oxysterols and other markers of oxidative stress, inflammation and malnutrition in the vitamin e and intima media thickness progression in end-stage renal disease (VIPER) cohort. Nephron Clin Pract 100, c111-119.

[26] Micheletta F, Natoli S, Misuraca M, Sbarigia E, Diczfalusy U, Iuliano L (2004) Vitamin E supplementation in patients with carotid atherosclerosis: reversal of altered oxidative stress status in plasma but not in plaque. Arterioscler Thromb Vasc Biol 24, 136-140.

[27] Micheletta F, Natoli S, Iuliano L (2004) Supplemented {alpha}-Tocopherol Apparently Does Not Enter the Plaque Compartment. Arterioscler Thromb Vasc Biol 24, E141-E142.

[28] Iuliano L, Micheletta F, Natoli S, Ginanni Corradini S, Iappelli M, Elisei W, Giovannelli L, Violi F, Diczfalusy U (2003) Measurement of oxysterols and alpha-tocopherol in plasma and tissue samples as indices of oxidant stress status. Anal Biochem 312, 217-223.

[29] Iuliano L, Micheletta F, Natoli S (2003) Bullous pemphigoid: an unusual and insidious presentation of breast cancer. Clin Oncol (R Coll Radiol) 15, 505.

[30] Violi F, Micheletta F, Iuliano L (2002) Antioxidants and Atherosclerosis. Eur Heart J vol. 4 Supplement B, B17-B21.

[31] Violi F, Micheletta F, Iuliano L (2002) How to select patient candidates for antioxidant treatment? Circulation 106, e195; author reply e195.

[32] Violi F, Micheletta F, Iuliano L (2002) MRC/BHF Heart Protection Study. Lancet 360, 1782-1783; author reply 1783-1784.

[33] Violi F, Iuliano L, FitzGerald GA (2002) Vasomotor effects and pathophysiologic relevance of F-2-isoprostane formation in vascular diseases. Journal Am Coll Cardiol 39, 554-555.

[34] Silvestro A, Scopacasa F, Oliva G, de Cristofaro T, Iuliano L, Brevetti G (2002) Vitamin C prevents endothelial dysfunction induced by acute exercise in patients with intermittent claudication. Atherosclerosis 165, 277-283.

[35] Iuliano L, Micheletta F, Violi F, Spagnoli LG (2002) Effect of ramipril and vitamin E on atherosclerosis. Circulation 105, E5-6.

[36] Ferro D, Iuliano L, Violi F, Valesini G, Conti F (2002) Antioxidant treatment decreases the titer of circulating anticardiolipin antibodies: comment on the article by Sambo et al. Arthritis Rheum 46, 3110-3112.

[37] Violi F, Micheletta F, Iuliano L (2001) Vitamin E, atherosclerosis and thrombosis. Thromb Haemost 85, 766-770.

[38] Violi F, Micheletta F, Iuliano L (2001) Vitamin E supplementation. Lancet 357, 632-633.

[39] Violi F, Micheletta F, Iuliano L (2001) Clinical trials with vitamin E in cardiovascular disease: are they meaningful? Thromb Haemost 86, 1121-1122.

[40] Iuliano L, Pratico D, Greco C, Mangieri E, Scibilia G, FitzGerald GA, Violi F (2001) Angioplasty increases coronary sinus F2-isoprostane formation: evidence for in vivo oxidative stress during PTCA. J Am Coll Cardiol 37, 76-80.

[41] Iuliano L, Micheletta F, Violi F (2001) Low-density lipoprotein oxidation. Ital Heart J 2, 867-872.

[42] Iuliano L, Micheletta F, Maranghi M, Frati G, Diczfalusy U, Violi F (2001) Bioavailability of vitamin E as function of food intake in healthy subjects: effects on plasma peroxide-scavenging activity and cholesterol-oxidation products. Arterioscler Thromb Vasc Biol 21, E34-37.

[43] Iuliano L, Micheletta F (2001) [Atrial fibrillation. Epidemiology and physiopathology.]. Haematologica 86, 1-4.

[44] Iuliano L, Gurgo A, Pranteda G (2001) Guess what! Malignant metastatic melanoma presenting with generalized melanosis and melanuria. Eur J Dermatol 11, 477-478.

[45] Iuliano L (2001) The oxidant stress hypothesis of atherogenesis. Lipids 36 Suppl, S41-44.

[46] Iuliano L (2001) Antioxidant therapy in vascular disease. Haematologica 86, 22-24.

[47] Pratico D, Iuliano L, Amerio G, Tang LX, Rokach J, Sabatino G, Violi F (2000) Down's syndrome is associated with increased 8,12-iso-iPF2alpha-VI levels: evidence for enhanced lipid peroxidation in vivo. Ann Neurol 48, 795-798.

[48] Iuliano L, Piccheri C, Coppola I, Pratico D, Micheletta F, Violi F (2000) Fluorescence quenching of dipyridamole associated to peroxyl radical scavenging: a versatile probe to measure the chain breaking antioxidant activity of biomolecules. Biochim Biophys Acta 1474, 177-182.

[49] Iuliano L, Mauriello A, Sbarigia E, Spagnoli LG, Violi F (2000) Radiolabeled native low-density lipoprotein injected into patients with carotid stenosis accumulates in macrophages of atherosclerotic plaque : effect of vitamin E supplementation. Circulation 101, 1249-1254.

[50] Iuliano L, Gurgo A, Polettini E, Gualdi G, De Marzio P (2000) Musculoskeletal and adipose tissue hydatidosis based on the iatrogenic spreading of cystic fluid during surgery: report of a case. Surg Today 30, 947-949.

[51] Iuliano L, Gurgo A, Licci S (2000) Granulocytic sarcoma in a non-leukemic patient presenting with unusual cutaneous paraneoplastic syndrome. Haematologica 85, 763.

[52] Iuliano L, Gurgo A, Gualdi G, Bonavita MS (2000) Succeeding onset of hepatic, splenic, and renal infarction in polyarteritis nodosa. Am J Gastroenterol 95, 1837-1838.

[53] Caccese D, Pratico D, Ghiselli A, Natoli S, Pignatelli P, Sanguigni V, Iuliano L, Violi F (2000) Superoxide anion and hydroxyl radical release by collagen-induced platelet aggregation--role of arachidonic acid metabolism. Thromb Haemost 83, 485-490.

[54] Pratico D, Pasin M, Barry OP, Ghiselli A, Sabatino G, Iuliano L, FitzGerald GA, Violi F (1999) Iron-dependent human platelet activation and hydroxyl radical formation: involvement of protein kinase C. Circulation 99, 3118-3124.

[55] Pratico D, Ferro D, Iuliano L, Rokach J, Conti F, Valesini G, FitzGerald GA, Violi F (1999) Ongoing prothrombotic state in patients with antiphospholipid antibodies: a role for increased lipid peroxidation. Blood 93, 3401-3407.

[56] Iuliano L, Pedersen JZ, Camastra C, Bello V, Ceccarelli S, Violi F (1999) Protection of low density lipoprotein oxidation by the antioxidant agent IRFI005, a new synthetic hydrophilic vitamin E analogue. Free Radic Biol Med 26, 858-868.

[57] Ferro D, Basili S, Pratico D, Iuliano L, FitzGerald GA, Violi F (1999) Vitamin E reduces monocyte tissue factor expression in cirrhotic patients. Blood 93, 2945-2950.

[58] Pratico D, Iuliano L, Basili S, Ferro D, Camastra C, Cordova C, FitzGerald GA, Violi F (1998) Enhanced lipid peroxidation in hepatic cirrhosis. J Investig Med 46, 51-57.

[59] Pratico D, Barry OP, Lawson JA, Adiyaman M, Hwang SW, Khanapure SP, Iuliano L, Rokach J, FitzGerald GA (1998) IPF2alpha-I: an index of lipid peroxidation in humans. Proc Natl Acad Sci U S A 95, 3449-3454.

[60] Davi G, Ferro D, Basili S, Iuliano L, Camastra C, Giammarresi C, Santarone S, Rocca B, Landolfi R, Ciabattoni G, Cordova C, Violi F (1998) Increased thromboxane metabolites excretion in liver cirrhosis. Thromb Haemost 79, 747-751.

[61] Basili S, Milani M, Longoni A, Vieri M, Iuliano L, Violi F (1998) Determinants of fibrinogen in an Italian population suffering from claudication. Lower fibrinogen in the south compared to middle and north of Italy. The ADEP Group. Haematologica 83, 701-707.

[62] Violi F, Iuliano L (1997) Antioxidants and ischaemic heart disease. Lancet 350, 667-668.

[63] Pratico D, Iuliano L, Mauriello A, Spagnoli L, Lawson JA, Rokach J, Maclouf J, Violi F, FitzGerald GA (1997) Localization of distinct F2-isoprostanes in human atherosclerotic lesions. J Clin Invest 100, 2028-2034.

[64] Leo R, Pratico D, Iuliano L, Pulcinelli FM, Ghiselli A, Pignatelli P, Colavita AR, FitzGerald GA, Violi F (1997) Platelet activation by superoxide anion and hydroxyl radicals intrinsically generated by platelets that had undergone anoxia and then reoxygenated. Circulation 95, 885-891.

[65] Iuliano L, Signore A, Violi F (1997) Uptake of oxidized LDL by human atherosclerotic plaque. Circulation 96, 2093-2094.

[66] Iuliano L, Pratico D, Ferro D, Pittoni V, Valesini G, Lawson J, FitzGerald GA, Violi F (1997) Enhanced lipid peroxidation in patients positive for antiphospholipid antibodies. Blood 90, 3931-3935.

[67] Iuliano L, Colavita AR, Leo R, Pratico D, Violi F (1997) Oxygen free radicals and platelet activation. Free Radic Biol Med 22, 999-1006.

[68] Iuliano L, Signore A, Vallabajosula S, Colavita AR, Camastra C, Ronga G, Alessandri C, Sbarigia E, Fiorani P, Violi F (1996) Preparation and biodistribution of 99m technetium labelled oxidized LDL in man. Atherosclerosis 126, 131-141.

[69] Iuliano L, Colavita AR, Camastra C, Bello V, Quintarelli C, Alessandroni M, Piovella F, Violi F (1996) Protection of low density lipoprotein oxidation at chemical and cellular level by the antioxidant drug dipyridamole. Br J Pharmacol 119, 1438-1446.

[70] Iuliano L, Pedersen JZ, Rotilio G, Ferro D, Violi F (1995) A potent chain-breaking antioxidant activity of the cardiovascular drug dipyridamole. Free Radic Biol Med 18, 239-247.

[71] Iuliano L, Pedersen JZ, Pratico D, Rotilio G, Violi F (1994) Role of hydroxyl radicals in the activation of human platelets. Eur J Biochem 221, 695-704.

[72] De Mattia G, Laurenti O, Bravi C, Ghiselli A, Iuliano L, Balsano F (1994) Effect of aldose reductase inhibition on glutathione redox status in erythrocytes of diabetic patients. Metabolism 43, 965-968.

[73] Violi F, Iuliano L, Balsano F (1993) Iron, platelet function, and coronary heart disease: a possible link? Circulation 88, 805-806.

[74] Pratico D, Iuliano L, Alessandri C, Camastra C, Violi F (1993) Polymorphonuclear leukocyte-derived O2-reactive species activate primed platelets in human whole blood. Am J Physiol 264, H1582-1587.

[75] Violi F, Leo R, Davi G, Pratico D, Iuliano L, Balsano F (1992) Thrombocytpenia and thrombocytopathia in liver cirrhosis. Platelets 3, 233-239.

[76] Pratico D, Iuliano L, Pulcinelli FM, Bonavita MS, Gazzaniga PP, Violi F (1992) Hydrogen peroxide triggers activation of human platelets selectively exposed to nonaggregating concentrations of arachidonic acid and collagen. J Lab Clin Med 119, 364-370.

[77] Iuliano L, Violi F, Pedersen JZ, Pratico D, Rotilio G, Balsano F (1992) Free radical-mediated platelet activation by hemoglobin released from red blood cells. Arch Biochem Biophys 299, 220-224.

[78] Iuliano L, Pratico D, Ghiselli A, Bonavita MS, Violi F (1992) Reaction of dipyridamole with the hydroxyl radical. Lipids 27, 349-353.

[79] Iuliano L, Pratico D, Bonavita MS, Violi F (1992) Involvement of phospholipase A2 in hydrogen peroxide-dependent platelet activation. Platelets 2, 87-90.

[80] Iuliano L, Pedersen JZ, Ghiselli A, Pratico D, Rotilio G, Violi F (1992) Mechanism of reaction of a suggested superoxide-dismutase mimic, Fe(II)-N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine. Arch Biochem Biophys 293, 153-157.

[81] Violi F, Pratico D, Iuliano L, Balsano F (1991) Dipyridamole potentiates the inhibition of platelet aggregation by aspirin (in human platelet rich plasma and whole blood). J Lipid Mediat 4, 61-67.

[82] Pratico D, Iuliano L, Ghiselli A, Alessandri C, Violi F (1991) Hydrogen peroxide as trigger of platelet aggregation. Haemostasis 21, 169-174.

[83] Iuliano L, Pratico D, Ghiselli A, Bonavita MS, Violi F (1991) Superoxide dismutase triggers activation of "primed" platelets. Arch Biochem Biophys 289, 180-183.

[84] Alessandri C, Germani M, Censi C, Rudelli G, Iuliano L, Servi M, Ghiselli A, Violi F (1991) Plasma thiobarbituric acid reactive substances a predictive marker of cerebral ischemia in patients at high risk? Acta Neurol Scand 83, 323-327.

[85] Violi F, Pratico D, Ghiselli A, Alessandri C, Iuliano L, Cordova C, Balsano F (1990) Inhibition of cyclooxygenase-independent platelet aggregation by low vitamin E concentration. Atherosclerosis 82, 247-252.

[86] Iuliano L, Violi F, Ghiselli A, Alessandri C, Balsano F (1989) Dipyridamole inhibits lipid peroxidation and scevnges oxygen radicals. Lipids 24, 430-433.

[87] Iuliano L, Ghiselli A, Alessandri C, Bonavita MS, Violi F (1989) Superoxide anion scavenging property of dipyridamole. Thromb Haemost 61, 149.

[88] Violi F, Ghiselli A, Iuliano L, Pratico D, Alessandri C, Balsano F (1988) Inhibition by picotamide of thromboxane production in vitro and ex vivo. Eur J Clin Pharmacol 33, 599-602.

[89] Violi F, Ghiselli A, Iuliano L, Alessandri C, Cordova C, Balsano F (1988) Influence of hydroxyl radical scavengers on platelet function. Haemostasis 18, 91-98.

[90] Violi F, Valesini G, Iuliano L, Ghiselli A, Falco M, Balsano F (1987) Anticardiolipin antibodies and prostacyclin synthesis. Thromb Haemost 57, 374.

[91] Violi F, Iuliano L, Alessandri C, Ghiselli A, Balsano F (1985) A simple method for evaluating platelet superoxide dismutase. Scand J Clin Lab Invest 45, 713-716.

[92] Violi F, Ghiselli A, Alessandri C, Iuliano L, Cordova C, Balsano F (1985) Relationship between platelet cyclooxygenase pathway and plasma malondialdehyde-like material. Lipids 20, 322-324.

[93] Violi F, Ghiselli A, Alessandri C, Frattaroli S, Iuliano L, Balsano F (1985) Activation of platelet cyclooxygenase by red cells in vitro. N Engl J Med 313, 1091-1092.

[94] Violi F, Alessandri C, Iuliano L, Ghiselli A, Perrone A, Balsano F (1985) Blood lipid profile in healthy subjects treated with ticlopidine. Atherosclerosis 58, 291-294.

[95] Violi F, Alessandri C, Iuliano L, Frattaroli S, Ghiselli A, Balsano F (1985) Malondialdehyde-like material and beta-thromboglobulin plasma levels in patients suffering from transient ischemic attacks. Stroke 16, 14-16.

[96] Violi F, Iuliano L, Alessandri C, Frattaroli S, Bonavita MS (1984) Beta-thromboglobulin plasma levels in common migraine. Thromb Haemost 51, 295.

[97] Violi F, Alessandri C, Iuliano L, Frattaroli S, Balsano F (1984) Blood coagulation consumption in a patient with autoimmune chronic active hepatitis. Haematologica 69, 449-453.

[98] Violi F, Alessandri C, Ferro D, Gallina G, Iuliano L, Balsano F (1984) Fibrinopeptide A behaviour in chronic active hepatitis patients. Haematologica 69, 655-660.

[99] Cordova C, Musca A, Violi F, Alessandri C, Iuliano L (1984) Apolipoproteins A-I, A-II and B in chronic active hepatitis and in liver cirrhotic patients. Clin Chim Acta 137, 61-66.

[100] Cordova C, Musca A, Violi F, Alessandri C, Ghiselli A, Iuliano L, Balsano F (1984) Influence of vitamin E on plasma malondialdehyde-like material in man. Thromb Haemost 51, 347-348.

[101] Musca A, Cordova C, Violi F, Alessandri C, Iuliano L, Perrone A, Trinchieri F, Gnecchi M (1983) [Behavior of the fibrinogen polymerization curve in patients with chronic respiratory insufficiency]. Clin Ter 106, 113-116.

[102] Cordova C, Musca A, Violi F, Alessandri C, Iuliano L, Trinchieri F, Gnecchi M (1983) [Effects of vitamin E administration on high-density lipoprotein cholesterol and on hypolipoproteinemia A2]. Clin Ter 106, 35-38.