Genetic diseases of the kidney

 
Citation
Title:
Genetic diseases of the kidney
Author:
Editor:
City:
Publisher:
Academic Press
Year:
2008
Volume:
No. of Volumes:
Edition:
Pages:
829
Series Volume:
Series Editor:
Series Title:
Translator:
Language:
English
URL:
DOI:
LCCN:
OCLC Number:
License
Select License
ISBN:
9780124498518
Last Updated:
October 13th, 2011
Abstract

Genetic Diseases of the Kidney identifies and analyzes genetic abnormalities causing renal diseases in human subjects. Although in a sense the genome contains all the instructions required for the formation of a phenotype, the information is encoded in an extremely complicated fashion. In primary genetic diseases, the genetic instruction specifies a phenotype clearly linked with a discreet lesion confined to the kidney. However, the genetic disturbance may be imbedded in a complicated physiologic ensemble, so that the nexus between the genetic disturbance and the phenotype may be obscured; in consequence, the causal sequence is extremely difficult to unravel. In many instances the renal disease is one component of a complicated systemic hereditary disease, either monogenic or polygenic. Indeed, renal disease may arise as the sum of minor inputs from many different, seemingly unrelated genes, so that the genetic contributions may be difficult to identify. Confounding the problem further are environmental influences, originating either in the chromosomal environment from modifier genes, or in the extra-chromosomal environmental from intrauterine or postnatal influences. These considerations have determined both the organization of the text as well as the detailed description of the genetic disorders and the physiologic derangements that emerge.

* Lays the essential foundation of mammalian genetics principles for medical professionals with little to no background in genetics
* Analyzes specific renal diseases - both monogenic disorders confined to the kidney as well as systemic diseases with renal involvement - and explains their genetic causes.
*World-renowned editors and authors offer expert frameworks for understanding the links between genes and complex clinical disorders (i.e., lupus, diabetes, HIV, and hypertension)


Seller Condition Item Price Shipping Total Cost
AlibrisUS$ 65.47 US$ 3.50US$ 68.97
AlibrisGood 0124498515 Good condition ex-library book with usual library markings and stickers.US$ 65.48 US$ 3.50US$ 68.98
AlibrisFair Buy with confidence. Excellent Customer Service & Return policy. Ships Fast. 24*7 Customer Service.US$ 90.86 US$ 3.50US$ 94.36
AlibrisUS$ 99.95 US$ 3.50US$ 103.45
AlibrisUS$ 120.24 US$ 3.50US$ 123.74
AlibrisUS$ 121.13 US$ 3.50US$ 124.63
AlibrisUS$ 135.65 US$ 3.50US$ 139.15
AlibrisUS$ 136.68 US$ 3.50US$ 140.18
AlibrisNew Buy with confidence. Excellent Customer Service & Return policy. Ships Fast. 24*7 Customer Service.US$ 249.75 US$ 3.50US$ 253.25
  • Recommend Us